Jayne Hesley is a Senior Applications Scientist for Cellular Imaging at Molecular Devices, LLC. She has over 10 years’ experience developing cell-based applications using ImageXpress Micro high content imaging systems and MetaXpress automated analysis software. Most recently her focus has been on exploring the use of 3D models, particularly cells or spheroids cultured in hydrogels, for studying cell viability, apoptosis, morphological changes, mitochondrial damage and autophagy. These studies include the use of automated confocal microscopy for live-cell timelapse experiments as well as screening assays in microplates. Prior to working in the imaging field, Jayne developed colorimetric and fluorescence assays, including TR-FRET and fluorescence polarization, for high-throughput screening on multi-mode readers. She has a B.S. in Animal Science and an M.S. in Biology.